Hyaluronidase (Hyalase)

Hyaluronidase is used to remove temporary fillers based on hyaluronic acid. Examples of this from our own practice are Teosyal, Stylage and Juvederm.

If too much of a hyaluronic acid filler has been used or not placed in the right place, this will lead to dissatisfaction with the result achieved. In the first instance, if it is placed by another clinic, we will refer you back to the attending physician. He / she can dissolve the filler if necessary. If it is a result of treatment with us, the costs are for our account. If you come to us and we have not done the treatment, costs will be charged.

Hyaluronidase effect?

Hyaluronidase is an enzyme that specifically removes hyaluronic acid.
A disadvantage of hyaluronidase can be that it can also dissolve some of your own naturally present hyaluronic acid. That is why we are careful with the use of hyaluronidase.

Hyaluronidase side effects.

As already mentioned, it is possible that some of your body’s own hyaluronic acid dissolves. By breaking down this intermediate connective tissue, your own connective tissue can also become more flexible. As a result, there may be a temporary loss of volume in the skin, which may become visible as a dent.

Hyaluronidase dosage

Due to the possible side effects, restraint with the use of hyaluronidase is desirable and we use it in the smallest possible quantities, working step by step towards the intended effect.
By dosing in this way we can ensure that the treated area becomes softer or that the hyaluronic acid is completely removed.

When does hyaluronidase not work?

Fillers that do not consist of hyaluronic acid, such as the obsolete permanent fillers (bioalcamid / silicone oil) and temporary fillers based on substances other than hyaluronic acid such as Sculptra and Radiesse cannot be dissolved with hyaluronidase! With these fillers, the treatment with hyaluronidase makes no sense.


The costs for a treatment can vary greatly, depending on how often and how much hyalase has to be used.
For patients who have not been treated in our practice, the costs start at € 120. For “own” patients the treatment is free as part of the total treatment.